简介：AbstractLung cancer continues to be the leading cause of cancer-related death in the world, which is classically subgrouped into two major histological types: Non-small cell lung cancer (NSCLC) (85% of patients) and small-cell lung cancer (SCLC) (15%). Tumor location has been reported to be associated with the prognosis of various solid tumors. Several types of cancer often occur in a specific region and are more prone to spread to predilection locations, including colorectal cancer, prostate cancer, gastric cancer, ovarian cancer, cervical cancer, bladder cancer, lung tumor, and so on. Besides, tumor location is also considered as a risk factor for lung neoplasm with chronic obstructive pulmonary disease/emphysema. Additionally, the primary lung cancer location is associated with specific lymph node metastasis. And the recent analysis has shown that the primary location may affect metastasis pattern in metastatic NSCLC based on a large population. Numerous studies have enrolled the "location" factor in the risk model. Anatomy location and lobe-specific location are both important in prognosis. Therefore, it is important for us to clarify the characteristics about tumor location according to various definitions. However, the inconsistent definitions about tumor location among different articles are controversial. It is also a significant guidance in multimode therapy in the present time. In this review, we mainly aim to provide a new insight about tumor location, including anatomy, clinicopathology, and prognosis in patients with lung neoplasm.

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简介：ObjectivesTodeterminethesafetyandvalueofesophagealradiographyasameansoflocatingtransseptalpuncture.Methods486patientswhounderwenttransseptalpuncturewererandomizedintotwogroups.Anesophagusradiographicmethodoflocatingtansseptalpuncturesitewasappliedinthestudygroup(n=243)andmodified-Rosslocatingmethodwasusedinthecontrolgroup(n=243).Aftersuccessfullocation,transseptalpuncturewasmade.Weobservedthesuccessrateandincidencecomplicationsinthe2groups.ResultsLeftatriumimpressioninthestudygroupwasclearlyseen.Nonethelessin120casesofcontrolgroup,theleftatriasilhouettewasnotclearlyvisualised.Thesuccessrateoflocatingtransseptalpuncturesiteinthestudygroupandcontrolgroupwere100%and50.6%respectively(P<0.001).Thesuccessrateoftransseptalpunctureinthestudygroupandcontrolgroupwas99.6%and45.7%respectively(P<0.001).Therewerenocomplicationsassociatedwithpunctureinthestudygroupandpericardialtamponadeoccurredin1controlpatient.ConclusionsTheesophagusradiographicmethodoflocatingtransseptalpuncturesiteisaccurate,safeandsimpletoperform.Transseptalpuncturehasahighsuccessratewithfewcomplications.

简介：我们与高风险的前列腺癌症在271个病人报导全面的率，地点和积极外科的边缘(PSM)的预兆的因素。在2008年4月和2011年10月之间，我们有希望地从作为D'Amico分类的病人收集了数据高风险经历了帮助机器人的laparoscopic激进分子前列腺切除术。PSM的全面的率和地点被报导。逐步的逻辑回归模型被适合估计PSM的预兆的因素。PSM的全面的率是25.1%(271个病人中的68个)。这些PSM，(68中的26个)38.2%是posterolateral(PL)，26.5%(68中的18个)multifocal，16.2%(68中的11个)在顶，14.7%(68中的10个)在膀胱颈，并且4.4%(3/68)在另外的地点。有病理学的阶段pT2的病人的PSM率是8.6%(140中的12个)，26.6%(64中的17个)pT3a，53.3%(32/60)pT4的pT3b，和100%(7中的7个)。在包括pre-，intra-，和手术后的参数的一个逻辑回归模型，身体团索引(机会比率[或]：1.09；95%信心间隔[CI]：1.01-1.19，P=0.029)，病理学的舞台(pT3b或更高对pT2；或：5.14；95%CI：1.92-13.78；P=0.001)并且肿瘤的百分比(或：46.71；95%CI：6.37-342.57；P<0.001)是为PSM的独立预兆的因素。在病人在的PSM的最普通的地点高风险是PL方面，它反映报导肿瘤攻击性。PSM的唯一的重要预兆的因素是病理学的结果，例如在标本和病理学的舞台的肿瘤的百分比。