简介：AIM：Toestablishaprognosticformulathatdistinguishesnon-hypervascularhepaticnodules（NHNs）withhigheraggressivenessfromlesshazardousone.METHODS：Seventy-threeNHNsweredetectedingadoliniumethoxybenzyldiethylene-triamine-pentaaceticacidmagneticresonanceimaging（Gd-EOB-DTPA-MRI）studyandconfirmedtochange2mmormoreinsizeand/ortogainhypervascularity.Allimageswereinterpretedindependentlybyanexperienced,board-certifiedabdominalradiologistandhepatologist;bothknewthatthepatientswereatriskforhepatocellularcarcinomadevelopmentbutwereblindedtotheclinicalinformation.AformulapredictingNHNdestinywasdevelopedusingageneralizedestimatingequationmodelwiththirteenexplanatoryvariables：age,gender,backgroundliverdiseases,Child-Pughclass,NHNdiameter,T1-weightedimaging/T2-weightedimagingdetectability,fatdeposition,lowersignalintensityinarterialphase,lowersignalintensityinequilibriumphase,α-fetoprotein,des-γ-carboxyprothrombin,α-fetoprotein-L3,andcoexistenceofclassicalhepatocellularcarcinoma.Theaccuracyoftheformulawasvalidatedinbootstrapsamplesthatwerecreatedbyresamplingof1000iterations.RESULTS：Duringamedianfollow-upperiodof504d,73NHNswithamediandiameterof9mm（interquartilerange：8-12mm）greworshrankby68.5%（fiftynodules）or20.5%（fifteennodules）,respectively,whereashypervascularitydevelopedin38.4%（twentyeightnodules）.Inthefifteenshranknodules,twelvenodulesdisappeared,while11.0%（eightnodules）werestableinsizebutacquiredvascularity.AgeneralizedestimatingequationanalysisselectedfiveexplanatoriesfromthethirteenvariablesassignificantfactorstopredictNHNprogression.Theestimatedregressioncoefficientswere0.36forage,6.51forlowersignalintensityinarterialphase,8.70or6.03forpositivityofhepatitisBvirusorhepatitisCvirus,9.37fordes-γ-carboxyprothrombin,and-4.05forfatdeposition.Aformulaincorpora

简介：Moststudiesaddressingthespecificityofmeridiansandacupuncturepointshavefocusedmainlyonthedifferentneuraleffectsofacupunctureatdifferentpointsinhealthyindividuals.Thisstudyexaminedtheeffectsofacupunctureonbrainfunctioninapathologicalcontext.Sixteenpatientswithischemicstrokewererandomlyassignedtotruepointgroup(trueacupunctureatrightWaiguan(SJ5))andshampointgroup(shamacupuncture).Resultsoffunctionalmagneticresonanceimagingrevealedactivationinrightparietallobe(Brodmannareas7and19),therighttemporallobe(Brodmannarea39),therightlimbiclobe(Brodmannarea23)andbilateraloccipitallobes(Brodmannarea18).Furthermore,inhibitionofbilateralfrontallobes(Brodmannarea4,6,and45),rightparietallobe(Brodmannareas1and5)andlefttemporallobe(Brodmannarea21)wereobservedinthetruepointgroup.Activationintheprecuneusofrightparietallobe(Brodmannarea7)andinhibitionoftheleftsuperiorfrontalgyrus(Brodmannarea10)wasobservedintheshamgroup.Comparedwithshamacupuncture,acupunctureatWaiguaninstrokepatientsinhibitedBrodmannarea5onthehealthyside.Resultsindicatedthatthealteredspecificityofsensation-associatedcortex(Brodmannarea5)ispossiblyassociatedwithacentralmechanismofacupunctureatWaiguanforstrokepatients.

简介：BACKGROUND:Functionalmagneticresonanceimaging(fMRI)isinitiallyusedforvisualcortexlocation.However,theapplicationoffMRIininvestigatingthedevelopmentofvisualpathwaylesionsneedstobefurtherobserved.OBJECTIVE:Thisstudyistolongitudiallyobservethedynamicchangesincorticalfunctionandwhitematterfibrousstructureofpatientswithvisualpathwaylesionsbybloodoxygenationleveldependent-functionalmagneticresonanceimaging(BOLD-fMRI)combinedwithdiffusiontensorimaging(DTI),andtoanalyzethecharacteristicsofbrainfunctionandstructuralrecombinationatconvalescentperiodoflesions.DESIGN:Randomizedcontrolledobservation.SETTING:DepartmentofRadiology,theGeneralHospitalofNanjingMilitaryAreaCommandofChinesePLA.PARTICIPANTS:Eightpatientswithunilateralorbilateralvisualdisordercausedbyvisualpathwaylesions,whoadmittedtoDepartmentofRadiology,theGeneralHospitalofNanjingMilitaryAreaCommandofChinesePLAfromJanuarytoSeptember2006wereinvolved,andservedasexperimentalsubjects.Thepatients,6malesand2females,wereaged16-67years.Theyhadvisualdisorderconfirmedbyclinicalexamination,i.e.visualpathwaylesion,whichwasfurtherdiagnosedbyMRorCT.Another12subjectsgenerallymatchingtothosepatientsofexperimentalgroupingender,ageandsight,whoreceivedhealthexaminationinsynchronizationwereinvolvedandservedascontrols.Thesubjectshadnohistoryofeyediseases.Theirbinocularvisualacuity(orcorrectedvisualacuity)wasover1.0.Bothroutineexaminationofophthalmologyandexaminationoffunduswerenormal.Informedconsentsofdetecteditemswereobtainedfromallthesubjects.METHODS:SignaExciteHD1.5Tmagneticresonanceimagingsystemwith16passages(GECompany,USA)andcoilwith8passageswereused;brainfunctionalstimulusapparatus(SAV-8800.MeideCompany)wasusedforshowingexperimentalmission.Attheearlystageandconvalescentperiodoflesions,thepatie

简介：PureAl2O3-2SiO2powderswerepreparedbysol-gelandcoprecipitationmethods,andtheiralkaliactivationreactivitieswerecompared.Thealkali-activationreactivityofthepowderpreparedbythesol-gelmethodwashigherthanthatofthepowderpreparedbythecoprecipitationmethod.Thepowderswereinvestigatedby27AIand29Simagic-anglespinningnuclearmagneticresonancespectroscopy（MASNMR）tounderstandtherelationshipbetweentheirstructureandalkali-activationreactivity.The27AlMASNMRdatashowedthatthefive-coordinateAIcontentofthepowderpreparedbythesol-gelmethodwashigherthanthatofthepowderpreparedbycoprecipitation.Thehighercontentoffive-coordinateAlcorrespondedtohigheralkali-activationreactivity.The29SiMASNMRdatashowedthatforthepowderpreparedbythesol-gelmethod,siliconwasreplacedbyaluminumatsecondarycoordinationsitesofthecentralSiatomsduringcalcination.However,forthepowderpreparedbysingle-batchcoprecipitation,themainchangewasfromalowdegreeofpolycondensationtoahighdegreeofpolycondensation.