简介:Homochiralcis,cis-;cis,trans-andtrans,trans-spiro[4.4]nonane-1,6-diolswerepreparedviadiastereoselectivereductionofenantiomericallypurespiro[4.4]nonane-1,6-dione(1)withthecorrespondingreducingagents:lithiumn-butyldiisobutylaluminiumhydrideforcis,cis-diol(2)with88%yield;BH3·THFforcis,trans-diol(3)with91%yield;LiAlH4fortrans,trans-diol(4)with15%yield.
简介:Aseriesofnovel(S,S)-2,8-diazabicyclo[4.3.0]nonanecontainingbenzimidazolemoietywassynthesizedandtheirstructuresweredeterminedby1HNMRandHRMS.ThebiologicalactivityresultsshowedthatthesecompoundspossessedmoderateantifungalactivitytosomeplantpathogenousfungiandmoderateinsecticidalactivityagainstMythimnaseparataWalkerandCulexpipienspallens.Compounds6eand6fexhibitedgoodantibacterialactivityagainstSclerotiniasclerotiorum,PhytophthorainfestansandFusariumgraminearum.Thelethalityratesofcompounds6eand6kagainstMythimnaseparataWalkerwere100%at200mg/Landthelethalityratesofcompounds6hand6kagainstC.pippienspallenswere75%at2mg/L.
简介:你知道不莱梅吗?噢——它是一个美丽快乐的地方。不莱梅在哪儿呢?噢——有梦想的地方就有不莱梅。没错儿,不莱梅这个地方,早就存在于“很久很久以前”的童话里了……