简介：AbstractBackground:Fourier transform infrared (FTIR) spectroscopy technique has not been used as a diagnostic tool for diabetes in clinical practice. This study was linked to structural changes in hemoglobin (Hb) in type 2 diabetes patients at higher levels of HbA1C using FTIR spectroscopy.Methods:Fifty-three diabetic patients from the Bahawal Victoria Hospital, Bahawalpur, Pakistan were categorized as group A (6% < HbA1C < 7%; n = 25) and group B (HbA1C ≥9%; n = 28). Another group (group N) of twenty blood samples was taken from healthy people from the Islamia University Bahawalpur, Pakistan. Data from all groups were collected from January 1, 2018 to March 31, 2019. The structure of Hb was studied by FTIR spectroscopy and impact of glucose on the fine structure of HbA1C was estimated.Results:Hb secondary structure erythrocyte parameters were altered by changing glucose concentrations. From FTIR spectra of all three groups it was found that Hb structure was slightly altered in group A, but significantly changed in group B (P < 0.05). There was an increase in β-sheet structure and a reduction in α-helix structure at elevated levels of HbA1C (group B) in type 2 diabetes.Conclusion:We suggest that higher level of glycation reflected by increased HbA1C might be a contributing factor to structural changes in Hb in type 2 diabetic patients. FTIR spectroscopy can be a novel technique to find pathogenesis in type 2 diabetes.

简介：Severalaspectsoftheapplicationofsilverelectrodetotheelectrochemicalstudiesofhemoglobinhavebeendiscussedinthispaper.Thesilverelectrodecouldnotonlybeuseddirectlyastheelectrodefortheelectrochemicalstudiesofhemoglobin,butalsoreactwithphenothiazineandbenzimidazoletogivestableandusefulmediator-coatedelectrodes.Inaddition,thesilverelectrodecouldhelpsodiumdodecylsulfatetogivefullplaytoitspromotingeffectontheprotein.

简介：ＦＲＵＩＴＦＵＬＲＥＳＵＬＴＳＤｕｒｉｎｇｔｈｅｉｒｈａｌｌ－ａ－ｍｏｎｔｈｖｉｓｉｔｔｏＴｉｂｅｔ，ｔｈｅＣｏｌｏｒｆＵｌＣａｕｓｅｇｒｏｕｐｓｉｇｎｅｄｓｏｍｅ４０ｃｏｎｔｒａｃｔｓ，ａｇｒｅｅｍｅｎｔｓａｎｄｌｅｔｔｅｒｓｏｆｉｎｔｅｎｔ．Ｔｈ...

简介：Itiscommonlyseenthatpatientswithbonefractureoftencomplicateotherpartsofinjuriesthatpresentamoreurgentsituationthanfracturesandoftenneedtimelyrecognitionandmanagement.SinceDecember1998,wehavedetectedandanalyzedtheratioofwhitebloodcells(WBC)andhemoglobin(Hb)indiagnosisofcomplicatedinjuriesinpatientswithbonefractureandtrytoraiserescuerateandreducemisseddiagnosisrate.

简介：钴hexacyanoferrate(CoHCF)nanoparticle(尺寸ca。60nm)化学上修改的电极(CME)被制作，在这nanosizedCoHCFCME的血红素(Hb)的电气化学的行为被学习。与一个赤裸的玻璃质的碳电极(GCE)和以一种传统的方式的一般CoHCFCMEelectrodeposited比较，现在的nanosizedCoHCFCME高效地与相对高的敏感，稳定性，和longlife为Hb执行了electrocatalytic减小。与液体层析(LC)结合了，nanosizedCoHCFCME在确定的流动注射被用作Hb的电气化学的察觉者分析电气化学的决心(FIA-ECD)系统。山峰水流是在从2.5楳?景映牯業?捡摩映潲?慣'R湯搠潩楸敤愠摮栠摹潲敧?獵湩?的范围的集中的线性功能?楳楬慣椠浭扯汩穩摥爠瑵敨楮浵挠瑡污獹?獡瀠敲畣獲牯栠獡戠敥?瑳摵敩?湩搠晩敦敲瑮爠慥瑣潩?潣摮瑩潩獮?桔?敲?瑬?敲敶污摥琠慨?桴?佔?琨牵?癯牥映敲畱湥祣?景?佃?愠档敩敶????栠?漠?浩潭楢楬敺?畲桴湥畩?慣慴祬瑳渠慥?桴?牣瑩捩污瀠敲獳牵?潰湩?景??眠瑩??瀠敲獳牵?景???慐?敲捡楴湯琠浥数慲畴敲漠吗？？？？

简介：在低CTAB集中的血红素(Hb)的性质上的cetyltrimethylammonium溴化物(CTAB)的效果被紫外力的光谱，荧光，希腊语的第六个字母潜力，电导率和否定染色的传播电子显微镜(TEM)的方法在Hb/acyclovir/CTAB系统学习。随CTAB集中，在276nm的紫外山峰紧张，内在的荧光，Hb的希腊语的第六个字母潜力和系统的增加，电导率都被提高。Hb容易被氧化到oxyHb和hemichrome。在Hb/acyclovir/CTAB，Hb的系统，成为紫外力的光谱的CTAB，荧光，电导率和符合构造趋于原来的Hb被还给那些但是不那么做的希腊语的第六个字母潜力。Hb-acyclovir建筑群的紫外吸收山峰消失了，并且acyclovir引起的Hb的紧密的结构是refolded。当CTAB集中比5高时；

简介：BackgroundIncreasedlevelofglycatedhemoglobin(HbA1c)isassociatedwithhigherincidenceofcoronaryarterydisease(CAD)inthediabetics.However,therelationshipbetweenHbA1candtheriskofcoronaryarterystenosisinthenon-diabeticsiscontroversial.MethodsAretrospectiveresearchwasconductedon338enrolledparticipantswhohaveundergone2timesofcoronaryangiographicexaminationwithinthepastyear.Clinicalandlaboratoryvariablesattheinitialandthesecondtimeofadmissionwerecollected.AccordingtotheinitialmedianHbA1clevel,allparticipantsweredividedintotwogroupsnamedlowerandhighergroups.TherelationshipbetweenHbA1clevelandtheriskofcoronaryarterystenosisovertimewasevaluated.ResultsTheinitialvaluesofHbA1cinloweranduppergroupswere5.78±0.35%and6.21±0.32%(P<0.05).Ascomparedtothelowergroup,thepercentagesofmaleandsmokingparticipants,andtheserumlevelofCRPweresignificantlyhigherinthehighergroup(P<0.05).Othertraditionalriskfactorswerecomparablebetweenthetwogroups.Therewere54.2%and55.2%participantswithsinglevesselstenosis,and45.8%and44.8%withmultiplevesselstenoses,respectivelyinthetwogroupswithoutsignificantdifference.Thesecondtimeofadmission,were308.5±25.4days(lowergroup)and300.7±30.1days(highergroup)fromtheinitialadmission.AlthoughnosignificantchangesofHbA1clevelwereobservedwhencomparedtoinitial,HbA1clevelinthehighergroupwasstillsignificantlyhigherincomparisontothelowergroup(6.24±0.39%vs.5.80±0.36%,P=0.008).Thepercentageofnewcoronaryarterystenosis(≥50%stenosis)washigherinthehighergroupthanthatinthelowergroup(41.7%vs.32.3%,P<0.001).MultivariateregressionanalysessuggestedthatHbA1cremainedindependentfactorassociatedwithcoronaryarterystenosesafterextensiveadjustmentforriskfactors.ConclusionInthenondiabetics,increasedbaselineHbA1clevelportendstheriskofcorona

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简介：在这份报纸，我们在Rn上为Hormander鈥檚拉普拉斯算符考虑主要特征值问题，并且我们为如此的主要特征值发现一个比较原则。我们也在整个Rn学习一个相关半线性的亚elliptic方程并且证明在一个合适的条件下面，我们无穷地有这个问题的许多积极答案。关键词主要特征值-Hormander鈥檚拉普拉斯算符-积极答案先生(2000)题目分类35J65-35H20这个工作被中国的钥匙973工程部分地支持

简介：Inthispaper,wegivesomeresultonthesimultaneousproximinalsubsetandsimultaneousChebyshevintheuniformlyconvexBanachspaceAlsowegiverelationbetweenfixedpointtheoryandsimultaneousproximity.

简介：由一个大学倡导的激励性教育工程正在改变老师们的教学方法，但最重要的是学生们的学习方法。综述：当我们认为我们已经达到创造性教育边缘的时候，新的软件和硬件设施的出现使教与学的方式和策略得到创新。可以肯定的是，这些创新是教育者他们自己创造的。

简介：为meromorphic功能f，让至少表示顺序l的零f的数的功能。让f是nonconstantmeromorphic功能，以便。表示F=fn。假定F和F分享1厘米。如果(1)n3，或，那么，F=F，和f假定形式

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简介：Theresistanceseenintotheportinann-cubeformedbytwoverticesofdistancen-1isexactlyformulatedforanyposiiveintegern.Theresistancesseenintotheportinann-cubeformedbyanytwoverticesisalsofoundbyexperimentsfor1≤n≤7.

简介：HL-2Atokamakisthefirstnon-circularcross-sectiontokamakwithdivertorinChina.ApartfromboundarytransportandSOLstudy,theHL-2AmajorsubjectistoinvestigatetheimprovementofconfinementwithhighparametersandalotoffrontphysicsandrelevantengineeringtechniquesbyuseofitsspecialCloseddivertorwithlargevolumeinChina.

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简介：§1.IntroductionLet(Q,&~,P)beaseparableprobabilityspacewith&~=a(An>n>l),^beasubo-fieldof&~.SetandF*-E\.Ima.g..(2)ByFollmerLemma(o.f.[1],Th.3.5andTh.3.7),wemayassumethatwehavechosenaversionof(Ft)t><>suchthatforallw,F.(w}isarightcontinuousincreasingfunctionwithF0(w~)=0andFt(w}=1forallt^-~-.(Suchaversionof￡(Ft)canalsobeconstructedbyelementarymethod.)Forafixedw,denoteby

简介：Lastyears,severalexperimentsabouthalonucleiwereperformedatRIBLL.OntheanalyzingandfittingthedatabyusingGlaubertheorywithsomeassumptions,followingsomeresultswerededuced.1.~8Bshowsaprotonhalostructure.ThereactioncrosssectionσRof54MeV/u~8BonSiwasmeasuredas1634±49mb.Thedensitydistributionof~8BwasstudiedthroughafittingprocedureontheenhancementoftheσRatlowenergiesincludingthehighenergydatabyusingGlaubertheory.Theresultshowsalongtail...

简介：作者学习meromorphic地图砰的唯一的问题并且获得部分在2006改进Yan和陈的二条定理的二结果。

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