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简介:【摘要】目的:分析4R危机理论护理模式在重症肺炎(SP)患者中的应用效果。方法:选取收治于本院的70例SP患者,进行随机分组,对照组35例开展常规护理,观察组35例在此基础上,围绕4R危机理论,实施护理干预,就两组病情[急性生理和慢性健康(APACHE-Ⅱ)评分系统]进行评定,且对比两组风险事件发生情况。结果:与对照组相比(出院前),观察组APACHE-Ⅱ评分更低(P<0.05)。较之对照组(20.00%),观察组(2.86%)风险事件发生率更低(P<0.05)。结论:通过对SP患者实施4R危机理论下的护理措施,能显著改善其病情,减少风险事件发生。
简介:摘要目的探讨KLF4、Sp1、Notch1在胃癌中的表达关系,揭示其与胃癌病理学的相关性.方法本次研究中使用免疫组织化学法分析15例正常组织样本3和50例胃癌组织样本中KLF4、Sp1及Notch1蛋白水平,并分析三者4表达水平与胃癌临床病理间的相关性.结果5在胃癌组织中KLF4、Sp1及Notch1阳性表达率显著高于正常组(P<0.05);KLF4在高、中、低分化型胃癌组织中的阳性率分型间差异具有统计学意义(P<0.05),Sp1及Notch1在高、中、低分化型胃癌组织中的阳性率差异无统计学意义(P>0.05);淋巴转移组患者其KLF4、Sp1及Notch1阳性率均显著高于无转移组(P<0.05).不同临床样本分级患者间KLF4、Sp1及Notch1阳性率差异存在统计学意义(P<0.05).结论KLF4、Sp1、Notch1在胃癌的病发及发展的病理学过程中起着十分重要的作用,且可能成为下一代治疗胃癌的全新靶点,为胃癌的临床治疗提供新的途径.关键词KLF4;Sp1;Notch1;胃癌病理;相关性AbstractObjectiveToinvestigatetheexpressionof,Sp1andKLF4ingastriccancer,andtorevealthecorrelationbetweentheexpressionof,Notch1andgastriccancer.MethodsthelevelsofSp1,Notch1andKLF4proteinin50casesofgastriccancertissueswereanalyzedbyimmunohistochemicalmethodin15casesofgastriccancertissues,andthecorrelationbetweenthethreeandtheclinicalpathologyofgastriccancerwasanalyzed.ResultsthepositiveratesofNotch1,Sp1andKLF4weresignificantlyhigherthanthoseinnormalgroup(P<0.05),KLF4,Notch1andSp1inhigh,mediumandlowdifferentiatedgastriccancertissuesweresignificantlyhigherthanthoseinnormalgroup(P>0.05).ThepositiveratesofP<0.05,Notch1andKLF4weresignificantlyhigherthanthosewithoutmeGtastasis(Sp1).ThereweresignificantdifferencesinNotch1,Sp1andKLF4amongdifferentclinicalsamples(P<0.05).ConclusionKLF4,Sp1andNotch1playanimportantroleinthepathologicalprocessofgastriccancer,andmaybecomeanewtargetforthenextgenerationofgastriccancer,andprovideanewwayforthecliKniecyalwotrrdesatmentofgastriccancer.KLF4;Sp1;Notch1;gastriccancerpathology;correlation中图分类号R735.2文献标识码B文章编号1008-6315(2015)12-0790-026
简介:From1990to2001,theauthortreated31casesofurinaryretentionofposthemorrhoidectomyorcesareansectionwithacupunctureofHegu(LI4)(reinforcingmethod)andSanyinjiao(SP6)(reducingmethod).Thetherapeuticeffectofthetreatmentwassatisfactory,thetotaleffectiveratewas96.7%.Followingisthereportofthetreatment.
简介:CambodiaKiriro1stCascadeHydropowerStationisthefirstoverseasBOTprojectoftheStatePowerCorporation(SP).ItisareconstructionprojectwhichiscontractedbyChinaPowerTechnologyImport&ExportCompany(CPTIEC).OnDecember9,2000,theagreementonseller’sexportcreditloanconcernin
简介:BymeansofthetheoryofharmonicmapsintotheunitarygroupU(N),theauthorsstudyharmonicmapsintothesymplecticgroupSp(N).Thesymplecticunitonandsymplecticex-tendedunitonareintroduced.ThemethodofthesymplecticBacklundtransformationandtheDarbouxtransformationisusedtoconstructnewsymplecticunitonsfromaknownone.