简介：摘要目的对联合运用劳拉西泮与帕罗西汀药物在广泛性焦虑症治疗中的临床使用效果进行探讨.方法按随机数字表法,将８２例广泛性焦虑症患者均分成实验组与参照组,前者予以劳拉西泮与帕罗西汀治疗,后者仅给予帕罗西汀治疗,且比较２组患者的治疗效果.结果实验组患者的总有效率(９７．６％)比参照组患者(９０．２％)高,差异显著,有统计学意义(P＜０．０５);实验组患者治疗后的SAS、HAMA评分低于本组治疗前及参照组,差异存在统计学意义(P＜０．０５).结论对广泛性焦虑症患者予以劳拉西泮与帕罗西汀联合治疗,疗效确切,且可改善患者的焦虑状况,值得在临床上大力推广.关键词广泛性焦虑症;劳拉西泮;帕罗西汀GeneralizedanxietydisorderbylorazepamcombinedwithPaRossiDeantreatmenteffectAbstractobjectiveToexploretheclinicaleffectofthecombineduseofdrugsLauraSiandparoxetineinthetreatmentofpatientswithgeneralizedanxietydisorder．MethodsAccordingtotherandomnumbertablemethod,８２patientswithgeneralizedanxietydisorderweredividedintoexperimentalgroupandtherefＧerencegroup,theformerwastreatedwithLauraSiandPaRossiDean,thelatteronlygivenPaRossiDeantreatment,andcomparedthetreatmenteffectof２groupsofpatients．ResultsThetotaleffectiverate(９７．６％)ofthepatientsintheexperimentalgroupwassignificantlyhigherthanthoseinthecontrolgroup(９０．２％),whichwasstatisticallysignificant(P＜０．０５);theSASandHAMAscoresoftheexperimentalgroupweresignificantlylowerthanthoseinthetreatmentgroupandthecontrolgroup(P＜０．０５)．ConclusionLorazepamcombinedwithparoxetineinthetreatmentofpatientswithgeneralizedanxietydisorder,curativeeffectisexact,andcanimprovetheanxietyofpatients,itisworthpopularizinginclinic．KeywordsGeneralizedanxietydisorder;LauraSi;paroxetine中图分类号R７４９．７文献标识码B文章编号１００８－６３１５(２０１５)１２－１２９４－０２