简介：ThemethodofproducingacompleteMRIimageisbasedontheanalysisoffreeinductiondecay.ItmainlystudieswhenandhowmagneticvectorrevestsitsinitialstateafterRFpulse,butneglectstheeffectoftheRFform.Inthispaperwemainlystudythis.WegivethemathematicexpressionofRFpulsewhichcantheoreticallyimproveimage（?）ality.InMRI,B1（t）isthealternateelectromagneticexcitationfield,itcanbeexpressedasfollows:

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简介：BackgroundPulseoximetryscreening(POS)hasbeenproposedasaneffective,noninvasive,inexpensivetoolallowingearlierdiagnosisofcriticalcongenitalheartdisease(CCHD).However,mostneonatesaredischargedfromthehospitalwithoutthisevaluationinChina.ThisstudyaimedatassessingthefeasibilityofPOSfornewbornsindetectingCCHDinthedepartmentofobstetricsandneonatalintensivecareunit(NICU).MethodsPOSwasperformedin355neonatesborninthedepartmentofobstetricsoradmittedtotheNICUbetweenJanuary2015andJune2015.Theseneonatesweredividedintonormalgroup,mildcongenitalheartdiseasegroup(MCHD)andCCHDgroup,accordingtotheresultofechocardiographyorcomputerizedtomography(CT).Thegestationalage,birthweightandarterialoxygensaturation(SpO_2)werecomparedamongthethreegroups.TheSpO_2valueanddiagnosistimeoftheCCHDcaseswereclassifiedandanalyzed.ResultsTheprematurebirthandlowbirthweightwerethehighriskfactorsofmildcongenitalheartdisease.Therewasnodifference(P>0.05)inSpO_2betweentheMCHDgroupandthenormalgroup.SignificantdifferenceintheSpO_2appearedbetweentheCCHDgroupandthenormalgroup(P<0.05).CombinationofPOSandclinicalexaminationcanreducethemissingdiagnosisrateinscreeningforCCHD.ConclusionsPOSincursverylowcostandriskofharmandisnotrequiredforspecialtraining,therefore,aneffectivewaytoidentifyCCHDinneonates.

简介：Gapinducedpie-pulseinhibition(Gap-PPI)ofacousticstartlereflexhasbeenusedasameasurementoftinnitusinanimalmodels.However,whetherthistestissensitivetodetecttinnitusinhumansisstillunclear.Basedonthetestingprocedureusedinanimalstudies,ahumansubjecttestingmethodwasformulatedandconductedtoinvestigateifasimilarresultcouldbefoundintinnituspatients.Audiologicandtinnitusassessmentsandacousticstartlereflexmeasurementswereperformedonseventinnitussubjectsandnineagematchedsubjectswithouttinnitus.TherewasnosignificantdifferencefoundbetweenthecontrolandtinnitusgroupontheGap-PPlacrossthefrequenciesevaluated.Theamplitudeofthestartleresponseinthetinnitusgroupwithnormalhearingthresholdswassignificantlyhigherthanthecontrolgroupandthosewithtinnitusandhearingloss.Thispreliminaryresultsuggeststhathyperexcitabilityinthecentralauditorysystemmaybeinvolvedintinnitus.Therewasnocorrelationbetweenhearingthresholdsandtheincreasedamplitudeofstartleresponse.

简介：这篇论文由脉搏感到在肿瘤的处理把简短介绍给了教授于的经验，它都通过整个针灸实践被进行。Wehope医生将在尝试在未来在脉搏诊断上做进一步、深入的研究揭示在脉搏和针灸之间的内在的关系提高临床的功效并且因此在肿瘤的治疗开创针灸的更宽广的空间。

简介：

简介：PulsediagnosisplaysavitalroleinTraditionalChineseMedicine(TCM).Toextracteffectiveandproperfeaturesfromthewrist-pulse-signalsisacrucialstepfortherecognitionandclassificationofthepulsesignals.Althoughtheanalysisinthetimedomainisalsoveryeffectiveforalotofpulsetypes(SHUetal.,2007),thefrequencyandtime-frequencyanalysisareusuallyusedintheliterature(YANetal.,2005;YUEetal.,2006)becausethepulsesignalsarenon-stationaryandnon-periodictimeseriesinthepathologicalstates.Inrecentyears,anewtime-frequencyanalysismethod,Hilbert-HUANGTransformproposedby

简介：

简介：BasedonthefuzzycharacteristicofthepulsestateandsyndromesdifferentiationthinkingmodeofTCM,aninformationfusingrecognitionmethodofpulsestatesbasedonSFNN(StochasticFuzzyNeuralNetwork)ispresentedinthispaper.Withthelearningabilityinparametersandstructure,SFNNfusesthemeasurementinformationofthreepulse-statesensorsdistributedinCun,Guan,andChilocationofbodyforthepulsestaterecognition.Theexperimentalresultsshowthatthepercentageofcorrectrecognitionwithnewmethodishigherthanthatbysingle-datarecognitionone,withfeweroff-linetrainnumbers.

简介：BackgroundIncreasedplasmalevelofLp-PLA2isapotentialriskfactorforatherosclerosis.Nevertheless,whetherLp-PLA2haseffectsonbothvascularfunctionandstructurechangesisstillunclear.MethodOnehundredandeighty-sixoutpatientsubjectswithoutovertcardiovasculardiseasewereenrolledandanthropometricdata,plasmalevelofLp-PLA2andotherrelatedlaboratoryparameterswerecollected.Measurementsofpulsewavevelocity(PWV)andcarotidintima-mediathickness(CIMT)wereperformedbyanexperiencedinvestigator.AccordingtoplasmalevelofLp-PLA2,allthesubjectsweredividedintotwogroupsasfollows:<200ng/mL(n=96)and≥200ng/mL(n=90).ResultBodymassindex,smoking,diabeticmellitus,systolicbloodpressure,andLDL-ClevelwerepositivecorrelationwithplasmalevelofLp-PLA2,whileuseofstatinswasnegativelycorrelative.BothPWVandCIMTpositivelycorrelatedwithsmoking,systolicbloodpressure,LDL-ClevelandplasmalevelofLp-PLA2,whilenegativelycorrelatedwithHDL-Clevelandusageofstatins.CIMTinthegroupwithplasmalevelofLp-PLA2<200ng/mL(0.9±0.2mm,n=96)wassignificantlylessthanthatwithplasmalevelofLp-PLA2≥200ng/mL(1.2±0.4mm,n=90,P=0.32),andsimilarfindingwasalsoobservedinPWV(9.1±0.5m/svs12.7±0.4m/s,P=0.38).ConclusionOurpresentstudyshowsthatinsubjectswithoutovertCVD,increasedplasmalevelofLp-PLA2isassociatedwithvascularfunction(PWV)andstructure(CIMT)deterioration.

简介：Objective:TostudythecharacteristicsofpulsetracingsinCHD,andobjectivelyevaluatethesignificanceofpulsesignalindiagnosisandappreciationoftherapeuticeffectinpatientswithcoronaryheartdisease(CHD),andaccordinglyprovidewiththeoreticproofsfordevelopingnon-invasivetechniqueofpulsediagnosis.Methods:Byusingthepulsedetectionsystem,pulsegraphsinCHDpatients,patientswithoutCHDand"health"adultswerecollectedandcompared.ThencharactersofthepulsesignalwereanalyzedwithHilbert-Huangtransformationroutine(HHT)andtime-domainmethodrespectively.Results:ThereexistedcharacteristicchangeinpulsegraphinCHD.①h1,h3,h4,h3/h1,t,t5/t4intimedomainparametersofpulsegraphincreasedandw1waswidened.②44%ofC2waveinHHTdisplayshowedchaoticanddisorderlywaveandirregularlywaveamplitudeinCHD.And72%ofC5Waveexhibitedinirregularwavewithaveragewaveamplitudeover10gram-forces.Thesechangesweresignificantlydifferentfromhealthadults.Conclusion:CharacteristicwaveofpulsegraphextractedwithmethodsoftimedomainorHHTroutinemightbeconsideredasproofsfordiagnosisanddifferentiationinCHD.OurresearchesprognosticatethatpulsediagnosiscanbeusedasanancillarydeterminationinoccurrenceofCHDforreasonsoftheadvantageofconvenientoperationandnon-invasion.

简介：ObjectivesEndothelialdysfunctionistheearliestmarkerforatherosclerosisandplayskeyroleinthepathogenesisofcardiovasculardiseases.Thepresentstudywasperformedtoevaluateeffectofagingonarterialelasticitybyusingpulsewaveformanalysisandinvestigatewhetherthechangesinarterialelasticitycanbeusedasanon-invasivemeasureforearlydetectionofendothelialdysfunction.MethodsUsingmodifiedWindkesselmodelofthecirculationandpulsewaveformanalysis,C1largearteryandC2smallarteryelasticityindicesof204normalhealthysubjects(age15-80years)weremeasured.Amongthemtwenty-fourmalehealthysubjectsweredividedintoboththeyoung(age20-30years,n=12)andelderly(age60-70years,n=12)groups.Wedeliveredacethycholine(Ach),anendotheliumdependentvasodilator,andsodiumnitroprusside(SNP),anendothelium-independentvasodilator,todermalvesselsoftheforearmusingiontophoresis,respectively,andmeasuredbasalandpeakbloodflowusinglaserdopplerfluximetry.ResultsC1largearteryandC2smallarteryelasticityindiceswerereducedwithadvancingage.C1largearteryandC2smallarteryelasticityindiceswerenegativelycorrelatedwithage(r=-0.628,p＜0.001;r=-0.595,p＜0.001).Basalbloodflowwassimilarbetweentheyoungandelderlygroups(14.58±3.4vs13.52±3.41PU,p=NS).PeakbloodflowinducedbyAchwassignificantlyreducedintheelderlygroupcomparedwiththeyounggroup(83.4±11.9vs93.75±10.87PU,p＜0.05).However,peakbloodflowinducedbySNPwassimilarinthetwogroups(119.17±16.76vs128.33±21.29PU,p=NS).Ach-inducedpeakbloodflowcorrelatedpositivelywithC1largearteryandC2smallarteryelasticityindices(r=0.56,p＜0.01;r=0.53,p＜0.01).ConclusionsAdvancingageleadstoimpairedarteryelasticityandendothelialdysfunction.Reducedarterialelasticityis,inparallel,associatedwithdiminishedendothelium-dependentvasodilation.Itisconcludedthata

简介：Brief-pulsestimulationat50Hzhasbeenshowntoterminateafterdischargesobservedinepilepsypatients.However,theoptimalpulsestimulationparametersforterminatingcorticalelectricalstimulation-inducedafterdischargesremainunclear.Inthepresentstudy,weexaminedtheeffectsofdifferentbrief-pulsestimulationfrequencies(5,50and100Hz)oncorticalelectricalstimulation-inducedafterdischargesin10patientswithrefractoryepilepsy.Resultsdemonstratedthatbrief-pulsestimulationcouldterminatecorticalelectricalstimulation-inducedafterdischargesinrefractoryepilepsypatients.Inconclusion,(1)abrief-pulsestimulationwasmoreeffectivewhentheafterdischargedidnotextendtothesurroundingbrainarea.(2)Ahigherbrief-pulsestimulationfrequency(especially100Hz)wasmorelikelytoterminateanafterdischarge.(3)Alowcurrentintensityofbrief-pulsestimulationwasmorelikelytoterminateanafterdischarge.