简介：目的：通过对Q值调整非球面切削与标准化LASIK术后视觉质量的观察来分析Q值引导个性化切削技术的临床效果。方法：对2008-01/05等效球镜低于-12.00D的46例88眼进行非球面切削或标准化LASIK术后进行随访,按术前屈光度数将其分为A组（〈-6.00D）和B组（-6.00～-12.00D）两组,对比各组非球面切削与标准化LASIK术后1mo裸眼视力、Q值、夜间眩光、夜间视物质量及满意率（后3者采取问卷调查）。结果：A、B组内非球面切削与标准化LASIK术后裸眼视力差异无统计学意义（t=1.18,P〉0.05;t=0.62,P〉0.05）;A、B组内非球面切削与标准化LASIK术后Q值差异无统计学意义（t=-0.93,P〉0.05;t=-0.372,P〉0.05）;A组内非球面切削与标准化LASIK术后眩光、夜间视物质量差异无统计学意义（眩光：χ^2=2.397,P＆gt;0.05;夜间视物质量：χ2=1.263,P〉0.05）;B组内非球面切削与标准化LASIK术后眩光、夜间视物质量差异有统计学意义（眩光：χ^2=10.85,P〈0.01;夜间视物质量：χ^2=10.85,P〈0.01）;术后效果满意率达到98％。结论：非球面切削能明显改善-6．00D以上的术后主观视觉质量。

简介：AIM:Todescribethecharacteristicsofmodulationtransferfunction(MTF)ofanteriorcornealsurface,andobtainthethenormalreferencerangeofMTFatdifferentspatialfrequenciesandopticalzonesoftheanteriorcornealsurfaceinmyopes.·METHODS:Fourhundredeyesfrom200patientswereexaminedunderSIRIUScornealtopographysystem.PhoenisanalysissoftwarewasappliedtosimulatetheMTFcurvesofanteriorcornealsurfaceatverticalandhorizontalmeridiansatthe3,4,5,6,7mmopticalzonesofcornea.TheMTFvaluesatspatialfrequenciesof5,10,15,20,25,30,35,40,45,50,55and60cycles/degree(c/d)wereselected.·RESULTS:TheMTFcurveofanteriorcornealsurfacedecreasedrapidlyfromlowtointermediatefrequency(0-15cpd)atvariousopticalzonesofcornea,thevaluedecreasedto0slowlyathigherfrequency(>15cpd).Withtheincreaseoftheopticalzonesofcornea,MTFcurvedecreasedgradually.3)Intherangeof3mm-6mmopticalzonesofthecornea,theMTFvaluesmeasuredathorizontalmeridianweregreaterthanthecorrespondingvaluesathorizontalmeridianofeachspatialfrequency,thedifferencewasstatisticallysignificant(P<0.05).At7mmopticalzonesofcornea,theMTFvaluesmeasuredathorizontalmeridianwerelessthanthecorrespondingvaluesatverticalmeridianat10-60spatialfrequencies(cpd),andthedifferencewasstatisticallysignificantin25,30,35,40,45,50cpd(P<0.05).·CONCLUSION:MTFcanbeusedtodescribetheimagingqualityofopticalsystemsatanteriorcornealsurfaceobjectivelyindetail.

简介：目的：观察波前像差引导LASIK与波前像差优化LASIK对全眼高阶像差在0.3滋m以下近视散光眼的疗效差异。方法：前瞻性病例系列研究。收集在我院就诊拟行LASIK手术的近视散光患者30例60眼。每位患者随机选取一眼接受波前像差引导的LASIK,对侧眼接受波前像差优化的LASIK。术后6mo观察患者的视力、屈光度、全眼高阶像差及暗光下对比敏感度。采用配对样本t检验和字2检验进行统计学分析。结果：术后6mo,波前像差引导组与波前像差优化组分别有93%及90%的术眼裸眼视力逸5.0,两组术后等效球镜值在±0.50D范围内的比例分别为87%及83%,差异无统计学意义（P〉0.05）。两组术后均未出现最佳矫正视力丢失2行或以上的情形。两组术后总高阶像差、球差、彗差均较术前增大（P〈0.01）,但增幅在两组间无统计学差异（P〉0.05）。两组术后6mo暗光下对比敏感度在各个空间频率均恢复至术前水平,差异无统计学意义（P〉0.05）。结论：对术前全眼高阶像差小于0.3滋m的近视散光眼,波前像差引导LASIK与波前像差优化LASIK对术后视力、屈光度、全眼高阶像差及对比敏感度的影响无明显差异。