摘要
【摘要】目的：以分组形式明确替硝唑联合盐酸米诺环素软膏在牙周病中的应用意义。方法：以 2009.1-2019.1为时间线，将研究主体设为我院收治的 78例牙周病患者。采取随机均分的形式分组，对照组（ n=39）单用盐酸米诺环素软膏治疗，观察组（ n=39）联合替硝唑以及盐酸米诺环素软膏进行治疗，基于牙菌斑指数、牙周袋深度、牙齿松动度等指标数据为依据评价两组治疗效果。结果：干预前牙菌斑指数、牙周袋深度、牙齿松动度两组相当（ P>0.05），在干预后两组呈现明显化差异，即观察组牙菌斑指数、牙周袋深度、牙齿松动度更低（ P<0.05）。结论：联合替硝唑以及盐酸米诺环素软膏对牙周病进行治疗，可有效改善患者牙周指标，疗效确切。
【关键词】替硝唑 ;盐酸米诺环素软膏 ;牙周病 ;疗效
[Abstract] Objective: to determine the clinical significance of tinidazole combined with minocycline hydrochloride ointment in periodontal disease. Methods: Taking January 2009 to January 2019 as the time line, 78 patients with periodontal disease in our hospital were selected as the research subjects. The control group (n = 39) was treated with minocycline hydrochloride ointment alone, and the observation group (n = 39) was treated with tinidazole and minocycline hydrochloride ointment. The treatment effect of the two groups was evaluated based on the plaque index, periodontal pocket depth, tooth mobility and other indicators. Results: before the intervention, the plaque index, periodontal pocket depth and tooth mobility of the two groups were similar (P > 0.05), but after the intervention, there were significant differences between the two groups, that is, the plaque index, periodontal pocket depth and tooth mobility of the observation group were lower (P < 0.05). Conclusion: the combination of Tinidazole and minocycline hydrochloride ointment in the treatment of periodontal disease can effectively improve the periodontal index of patients with definite curative effect.
出版日期
2020年10月12日（中国期刊网平台首次上网日期，不代表论文的发表时间）
