摘要
Thefructosemodifiedchitosanmicrocarries(CMs)werepreparedbythereactionofglutaraldehydewithfructose-modifiedchitosan.Variousfactorsthatinfluencethepreparationwerestudiedandthereactionconditionswereoptimized.MorphologyofrathepatocytesculturedonCMswasobservedusingphasecontrastmicroscopeandscanningelectronmicroscope,andthemetabolicactivitiesweremeasured.RathepatocytesculturedonCMsretainedthesphericalshapeastheyhaveinvivoandhadhighmetabolicactivities.FructosecanenhancethemetabolicactivityofhepatocytesandthemodifiedCMsarepromisingscaffoldforhepatocytesattachment.
出版日期
2004年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)