Does the use of recombinant TSH in preparation for I-131 scintigraphy scan affect hearing function?-中国期刊网

摘要 Objective:TheobjectiveofthisstudywastoexaminetheeffectofhypothyroidismonhearingfunctioninpatientssurgicallytreatedfordifferentiatedthyroidcancerandsubsequentlyexperiencedhypothyroidismduringpreparationforfollowupI-131scintigraphyscanbyeitherrecombinanthumanthyroidstimulatinghormone(rhTSH)treatmentorthyroidhormonewithdrawal(THW).Methods:Atotalof55patientsundergoingI-131scintigraphyscanfollowingsurgeriesfordifferentiatedthyroidcancerwereincludedinthestudy,including25patientspreparedbyadministrationofrecombinantTSH(rhTSHGroup)and30patientsbythyroidhormonewithdrawal(THWGroup).Results:Airconductionthresholdsat1,2and4kHzforbothearswerehigherduringhypothyroidperiodthanduringeuthyroidperiodforpatientsintheTHWgroup(p<0.05)butnotforpatientsintherhTSHgroup.Conclusion:Sensorineuralhearinglosswasdetected,especiallyatlowfrequencies,inpatientswithDTCaftersurgicaltreatmentwhosehormonereplacementtherapywaswithdrawnbutnotinthosereceivingrhTSH.ItisthereforepreferredtouserhTSHwhenpreparingforI-131scintigraphyscaninpatientsatriskforhearingloss.

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Does the use of recombinant TSH in preparation for I-131 scintigraphy scan affect hearing function?

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Does the use of recombinant TSH in preparation for I-131 scintigraphy scan affect hearing function?

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