摘要
Thispaperproposesa3-dimensionalcoarsegrainmodelofmicrotubulesandtreatsthetubulinmonomerasasphereofmultiplepatches,withparameterschosentoyieldexperimentalvaluesofbendingandstretchingstiffness.Themodelhasdemonstratedtheabilitytoproducethebistabilityoftubulinsheets,elasticdeformationnearthetip,andcrackingandpeelingofprotofilaments.Thismodelisexpectedtotakeintoaccountthestructuralandmechanicalaspectsunderlyingthephysicalmechanismofpolymerization/depolymerizationanddynamicinstabilityofmicrotubules.
出版日期
2012年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)