简介:【摘要】目的 分析多囊卵巢综合征接受降脂排卵方+环丙孕酮方案治疗疗效。方法 80例多囊卵巢综合征患者为样本,时间2020年10月-2021年10月,随机数字表法分组,观察组降脂排卵方+环丙孕酮治疗,对照组环丙孕酮治疗,对比疗效、脂质代谢指标差异。结果 观察组多囊卵巢综合征患者排卵期子宫内膜厚、排卵率、妊娠率均优于对照组,P<0.05;观察组多囊卵巢综合征患者核受体超家族转录因子(PPARα)、固醇元件裂解激活蛋白(SCAP)、碱性环螺旋亮氨酸核转录因子(EBP1-C)等脂质代谢指标均优于对照组,P<0.05。结论 降脂排卵方+环丙孕酮方案用于多囊卵巢综合征患者治疗中,可调节子宫内膜厚度及脂质代谢指标,还可提升排卵率、妊娠率,高效可行。
简介:[摘要] 目的 分析多西环素与阿奇霉素(Azithromycin,AZM)联合治疗支原体感染的效果。方法 选取我院从2023年1月起始,至2023年12月结束的50例支原体感染患者为研究对象,以随机数字表法将分为A、B两组,各25例。B组采用阿奇霉素单药治疗,A组在B组基础上联合多西环素治疗。比较2组临床疗效、不良反应发生率。结果 2组临床总有效率比较,A组96.00%(24/25)高于B组68.00%(17/25)(P<0.05);治疗后A组不良反应发生率0%(0/25)与B组16.00%(4/25)相比,(P<0.05)。结论 多西环素与阿奇霉素联合治疗支原体感染疗效显著,减少不良反应发生率。
简介:摘要目的:研究并分析盐酸米诺环素软膏联合碘甘油对牙周炎患者的临床效果及牙周指标的影响。方法: 2018年 7月 -2019年 8月收治牙周炎患者 100例,按随机数字法分为两组。结果:观察组各项指标明显低于对照组,差异均有统计学意义( P<0.05)。结论:盐酸米诺环素软膏联合碘甘油治疗牙周炎,可有效降低患者的炎性反应,促进牙周组织恢复,改善牙周情况。 关键词 牙周炎 ;盐酸米诺环素软膏 ;碘甘油 ;
简介: 【摘 要】目的:探究他克莫司与环磷酰胺治疗狼疮性肾炎的的效果和用药不良反应率。方法:纳入观察对象 40例(均确诊为狼疮性肾炎)进行实验研究,研究时间从 2015年 3月直至 2019年 5月。采用随机分组法,将观察对象分为甲乙两组,甲组 20例患儿使用他克莫司治疗,乙组 20例患儿采取环磷酰胺治疗。观察对比两组患儿治疗效果、不良反应发生情况。结果:甲组中 1例患儿疗效不明显,另外 19例均有改善,总有效率 95%;乙组中 5例疗效不明显, 1例病情恶化,另外 14例病情改善,总有效率 70%,两组间进行比较后得到 P<0.05。治疗后随访观察到,甲组患儿 1例出现尿痛的不良反应,乙组中有 6例,两组不良反应发生率的差异显著( P<0.05)。结论:狼疮性肾炎患儿在治疗过程中可应用他克莫司与环磷酰胺进行治疗,对比发现,他克莫司可以明显提升治疗的有效率,并且控制了患儿不良反应的出现,治疗安全性得到保障,临床应用效果理想,值得推广。 【关键词】他克莫司 ;环磷酰胺 ;狼疮性肾炎 ;效果 ;不良反应率 [Abstract] Objective: To explore the effect and adverse reaction rate of tacrolimus and cyclophosphamide in the treatment of lupus nephritis. Methods: 40 patients (all diagnosed as lupus nephritis) were included in the experimental study. The study period was from March 2015 to may 2019. The observation objects were randomly divided into two groups, group A (20 cases) was treated with tacrolimus, and group B (20 cases) was treated with cyclophosphamide. The treatment effect and adverse reactions of the two groups were observed and compared. Results: in group A, the curative effect of 1 case was not obvious, the other 19 cases were improved, the total effective rate was 95%; in group B, the curative effect was not obvious in 5 cases, 1 case was deteriorated, the other 14 cases were improved, the total effective rate was 70%, the comparison between the two groups showed that P < 0.05. After treatment, 1 case of adverse reactions occurred in group A and 6 cases in group B. There was a significant difference in the incidence of adverse reactions between the two groups (P < 0.05). Conclusion: tacrolimus and cyclophosphamide can be used in the treatment of children with lupus nephritis. Compared with cyclophosphamide, tacrolimus can significantly improve the efficiency of treatment, and control the occurrence of adverse reactions in children. The safety of treatment is guaranteed and the clinical application effect is ideal, which is worthy of promotion.